Andrew B. Goryachev

Activator-inhibitor patterns on the scale of biological cells

Activator-inhibitor systems have become a paradigm of pattern formation and have been extensively studied theoretically. Despite much effort, experimental evidence supporting their role in biological morphogenesis is still scant. I will present an overview of our work on a specific molecular module that physically implements the activator-inhibitor paradigm on the scale of a single cell and demonstrate its role in intracellular morphogenesis on the examples from distinct biological systems.